OOTO Replies
When Outreach detects an out of the office (OOTO) reply from one of your prospects in a sequence, that prospect will automatically be paused in the sequence. These OOTO replies will not count as a reply from your prospect and will not count toward your reply rate.
You'll notice that the tag on that prospect specifically says Paused (OOTO), and not just Paused.
For more information, see: